Filorga NCTF 135 and NCTF 135 HA: A Polyrevitalising Mesotherapy Overview

Filorga, the Parisian laboratory behind the NCTF range, has been a fixture of the medical aesthetic market since the early 1930s, though its polyrevitalising mesotherapy solutions are still less widely known outside Europe than some competing skinbooster brands. NCTF 135 and NCTF 135 HA are worth understanding on their own terms: a multi-ingredient formulation designed to rehydrate and revitalise compromised skin, distinct from single-ingredient HA skinboosters. This overview is educational and does not describe an injection protocol.

What NCTF Is

NCTF is a polyrevitalising mesotherapy solution combining hyaluronic acid with a substantial additional ingredient list — commonly cited at over fifty components, including vitamins, minerals, amino acids, coenzymes, nucleic acid bases and antioxidants. The formulation approach sits at the "cocktail" end of the skin-quality spectrum, closer in concept to mesotherapy than to a single-molecule HA skinbooster, and is positioned for skin that needs broad nutritional and hydrating support rather than volume.

NCTF 135 vs NCTF 135 HA

The two formulations differ principally in hyaluronic acid concentration. NCTF 135 contains a lower concentration of HA and is generally positioned for younger or less compromised skin, where the priority is a lighter revitalising effect. NCTF 135 HA contains a considerably higher HA concentration and is generally positioned for more mature or more visibly damaged skin, where a more intensive hydrating and plumping effect is wanted. Presentation also differs slightly: NCTF 135 is supplied in a kit including syringes and needles, while NCTF 135 HA is available either in the same kit format or, separately, as vials only.

Typical Indications

Practitioners commonly consider NCTF formulations for:

• General skin revitalisation in dull, dehydrated or sun-affected skin
• Fine lines associated with dehydration rather than volume loss
• Adjunctive support within a broader skin-quality programme, alongside HA skinboosters or biorevitalisers
• Patients seeking a course-based treatment rather than a single-session volumising filler

As with other mesotherapy-style treatments, results are typically described as building over a course of several sessions, and maintenance treatment forms part of ongoing skin-quality management.

A Note on Off-Label Interest

The antioxidant and nutrient-dense composition of NCTF has occasionally attracted interest in dermatological literature for uses beyond general skin revitalisation, including in the context of pigmentary skin conditions. This is not an established or approved indication, and vitiligo and related pigmentary disorders are complex, typically autoimmune conditions that require assessment and management by a dermatologist rather than an aesthetic mesotherapy programme. Practitioners should be cautious about extending NCTF's use, or its marketing, beyond its recognised role in skin revitalisation.

Where NCTF Fits on a Skin-Quality Menu

NCTF sits comfortably alongside other mesotherapy-style and HA-based skin-quality treatments, such as Filorga NCTF 135HA itself or Jalupro, giving practitioners a formulation-based option to complement cross-linked HA skinboosters. Choice between them generally comes down to patient skin condition, desired texture of effect, and whether a broader nutrient profile or a more concentrated HA effect is the priority.

The Takeaway

NCTF's value lies in its broad, multi-ingredient composition and its two-strength range, which lets practitioners match formulation to skin condition rather than offering a single generic revitalising product. Its recognised role is skin revitalisation and hydration — a strong offering in its own right, without needing to reach for unproven applications.

Compare polyrevitalising and skinbooster options in the skinboosters range.